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In this new world of interconnectedness through the web, the different research areas of neuroscience, bio-immunology and attachment theory are entering a dialogue to try to better our understanding and improve our mental and physical health. This paper looks into the relationship between the client's preoccupied attachment style, her body symptoms (chronic fatigue), and the co-regulatory relationship. It shows how a client who had symptoms of chronic fatigue has learnt to self-regulate through the course of her attachment based therapy and whose symptoms have dissipated.