You do not currently have permission to view the full text for this document. Please sign in to an account with an active subscription or contact support.
Fonagy, P., Rost, F., Carlyle, J-a., McPherson, S., Thomas, R., Fearon, R. M. P., Goldberg, D., & Taylor, D. .
Pragmatic randomized controlled trial of long-term psychoanalytic psychotherapy for treatment-resistant depression: the Tavistock Adult Depression Study (TADS). World Psychiatry, 14: 312-321. doi: 10.1002/wps.20267
See paper here: onlinelibrary.wiley.com
The following is a summary of the abstract of the above:
This study describes a randomised controlled trial to assess the efficacy of treating patients with long-standing, treatment-resistant depression with long-term psychoanalytic psychotherapy (LTPP) combined with “treatment-as-usual” (TAU—as specified by UK national guidelines) compared with using TAU alone. 129 patients referred to primary care were randomly allocated to the two modes of treatment which was given over a period of eighteen months. They were assessed both during the treatment and following it at twenty-four, thirty, and forty-two months. The evaluation used a range of measures: the Hamilton Depression Rating Scale, self-reported depression (Beck Depression Inventory—II), social functioning (Global Assessment of Functioning), subjective well-being (Clinical Outcomes in Routine Evaluation—Outcome Measure), and satisfaction with general activities (Quality of Life Enjoyment and Satisfaction Questionnaire). In both groups, complete remission on ending treatment was infrequent (9.4% in the LTPP group vs. 6.5% in the control group) as it was at the final forty-two month follow-up (14.9% vs. 4.4%). On ending treatment partial remission was not significantly greater for the LTPP than the control group (32.1% vs. 23.9%). Statistically significant differences however were noted during the follow-up period: at twenty-four months: 38.8% vs. 19.2%; at thirty months: 34.7% vs. 12.2%; and at forty-two months: 30.0% vs. 4.4%. In addition, the observer-based and self-reported depression scores and measures of social adju