This article reviews the chapter on Edith Jacobson and Otto Kernberg in Greenberg and Mitchell's (1983) classic volume. It summarizes both their mostly accurate overview of the proposals of these two psychoanalytic contributors, and points to some misunderstanding of them in Greenberg and Mitchell's critique. The article then clarifies Otto Kernberg's present views, and proposes a concept of human motivation that includes both its neurobiological basis and the secondary symbolic level of organization of experience and motivation. This proposal includes a reformulation of the origin of Freud's dual drive system, and stresses the concept of unconscious intrapsychic conflict as a core aspect of psychoanalytic theory.