The sick building syndrome occurs when employees collectively experience something in the building as making them physically ill. Traditionally the sick building syndrome has been the domain of physical scientists, who have localized their investigations to the physical entities of the workplace. However, in the two decades this phenomena has been studied little evidence has contributed to the belief that physical causes can be isolated. Recent studies are suggesting that we begin to investigate the psychological basis of the disorder. This paper investigates the sick building disease from a psychoanalytic perspective, that is, the psychodynamic issues in the workplace that underlie the abberation, factors in the workplace that increase susceptibility, and the unconscious functions the syndrome plays in the life of employees.