In the 100-year-old history of the Nobel Prize in medicine or physiology, there are several fields whose practitioners have not received the prize. Among the unlucky candidates for the Nobel Prize, Sigmund Freud (1856-1939) is probably the most prominent and best known. He is also the one proposed for the prize during the longest period of time, almost a quarter of a century, or more precisely, between 1915 and 1938. In this article I will examine the nominations of Freud and the evaluations of his work by what is perhaps the most science centered of medical institutions, the Nobel Committee for Physiology or Medicine. I will place these in the context of the reception of Freud's work by Swedish psychiatrists. Here the influence of the most prominent psychiatrist at the time, Bror Gadelius, deserves special attention.