According to Erich Fromm and a relational psychoanalytic approach, changing economic and social requirements always impact human beings and their psychic structure. Because globalization leads particularly to a blurring of boundaries and limitations, the formation of a new character orientation that is driven to construct reality anew without limitations can be observed as a reaction in progress. The pathogenic effects of globalization can be studied through the analysis of this new character formation and the uncovering of repressed, unconscious feelings that characterize the new personality type, especially in regard to their sense of identity, their way of relating to others, and their de facto loss of ego strength – in contrast to the enacted “ego unlimited.” Finally, some aspects of transference and countertransference, as well as some particular defense reactions with which we psychoanalysts are confronted in the treatment of patients suffering from the pathogenic effects of globalization, will be discussed.