Consciousness remains one of the great unresolved mysteries of contemporary science. The attempt to translate qualitative experiences, such as pain and psychological suffering, into semiological systems—whether inspired by physicalism or idealism—risks excluding the very essence of what they seek to reduce. This challenge necessitates the inclusion of subjectivity within reductionist doctrines, fostering dialog among various disciplines concerned with mental phenomena. This article reviews the different conceptualizations of consciousness in Freud's work and argues that there is a remarkable synergy between the psychoanalytic perspective and some key principles underlying neuroscientific models of mental experience.