An organ neurosis is described in which conflicts are represented both at the psychical and at the physiological level. Psychical symptoms centred round claustrophobia, but included extreme anxiety and compulsive blocking, gastro-intestinal symptoms, tachycardia, epistaxis, pharyngitis, coughing, dyspnoea, and delayed menstruation. Inhibited genital desires because of incest taboos and a masochistic conception of the sexual function, together with a desire to remain dependent, formed the basis of the symptoms. The author asks if these physiological symptoms, which have no demonstrable organic cause, may not in the course of time become organized into chronic physical changes, or whether such changes are dependent upon specific factors, such as constitutional predisposition or quantitatively stronger early fixations.