This paper, read at the 18th International Psycho-Analytical Congress in London, applies the author's earlier formulations concerning the genetic and economic factors of ego organization to some aspects of the schizophrenic process. Some aspects of schizophrenia may be accounted for in terms of the impairment not so much of the ego as of specific ego functions. Emphasis is laid on the fact that this effort to integrate certain well-known data about schizophrenic defence, object relations, language, and reality testing is made on the understanding that one aspect can be fully meaningful only in interrelationship with others already studied. Metapsychological hypotheses are used to bridge the gap between the instinctual and ego aspects and to establish connections between them. Insight is gained into the economic aspects of aggression in the normal and schizophrenic individual and into deficiencies in the primary autonomous factors in the ego which may represent one etiological element in the predisposition to schizophrenia.