The present volume of this valuable series contains interesting discussions which aim at the integration of biological, clinical, and psycho-analytic observations and theories. It is often insufficiently realized how much Cannon's concept of homeostasis and Freud's psychodynamics have in common. The paper 'Experimental Approach to Symptom Mechanisms in Psychiatric Patients' contributes to the knowledge of the physical concomitants of anxiety. The last third of the volume is taken up by a discussion of Kanner's 'early infantile autism' which is of great interest to psycho-analysts. Among those taking part were Kanner, Dancey, Clifford Scott, Eisenberg, and Keeler. Kanner assumes that those children are born with defective 'affective potentialities' and that emotional 'refrigeration' on the part of their parents further enhances this defect. Clifford Scott raises the question of the importance of the way the mother deals with the child's excretions.