The author reflects, in this opening speech of the IPA Berlin Congress, on some changes in the world, in Germany and in psychoanalysis in the 85 years that have elapsed since the previous congress in Berlin, in 1922. He emphasizes important developments in psychoanalytic theory and practice, research and applications to understand several wider realms. He also stresses the importance of psychoanalysis for the current discussion on the trans-generational effects of traumatic events, and connects all these aspects with the theme of the Congress-remembering, repeating and working through.