The signification of symptom is bound to the oedipal scenario in Freudian psychoanalysis. In other words, the relation of symptom as a signifier to the repressed object as the signified is determined according to a specific kind of transcendental familial antagonism. In addition to this oedipal relegation, the hermeneutic apparatus of the psychoanalysis disregards the heterogeneity and mutability of symptom in favor of two regulative axioms of unity and identity. Leaving aside transcendental oedipal principles, the present paper aims at explaining the symptom from an immanent point of view. This immanent approach is based on a theoretical constellation made out of some Deleuzian and Bakhtinian concepts. In this regard, the heterogeneity and mutability of the symptom are illustrated without being reduced to oedipal clichés. Accordingly, the symptom is described as a grotesque knot bringing together some heterogeneous elements. The heterogeneous elements involving in the symptom form a rhizomatic multiplicity irreducible to a unified complex or an underlying repressed truth. Also, the mutability of symptom is derived from the flexible and rhizomatic dimensions of the symptomatic multiplicity. The heterogeneous and mutable semiosis of the symptom brings it beyond the representational discourses, and highlights its generative and mutable aspects.