The ‘aural’ aspects and musicality of the analytic encounter have recently been reaffirmed by emphasizing the importance, in the analytic session, of both verbal and nonverbal exchange. The ‘Motherese’ sometimes considered to be ‘protomusical’ or ‘protolinguistic’, has also been the subject of extensive consideration since it represents the most archaic element of primitive human communication, close to what has been described as ‘musilanguage’ (Brown 2000, 2017.) Starting from these considerations, the author outlines the link between music, emotional system and Self structure. After dwelling on a brief description of the brain areas involved in listening to music, the author delves into an analysis of the interpsychic. Defining the realm of the interpsychic is not an easy task; it is simpler to imagine the interpsychic as a transit included in the space of psychic extension produced by interacting minds. Moreover, the author considers the ‘interpsychic’ not as a form of communication ‘towards’, but as an ‘in-between’ other than the analytic third. Music, which accompanies human beings from birth, should occupy a privileged place in this drive for transformative analytic change. Four clinical vignettes highlight the link between music, interpsychic exchange and social sharing.