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This article looks at the dialogue between some relational and intrapsychic models of psychoanalysis, regarding the autonomy of the self. The article describes how certain types of meditation—in particular, the realization process —can facilitate both the experience of internal cohesion, the sense of oneself as a separate being, and the experience of participating in a fluidly reciprocal self-world matrix. The article discusses how the experience of interiority that can be cultivated through meditation leads to the emergence of a subtle, qualitative sense of self and other; enables creativity; and increases one's openness to other people.