Our mutual imbeddedness is the foundation for the relational world we inhabit, underpinned by relationally induced changes in brain structure, relationally generated somatic changes, the inhabiting of each other’s mirror neurons, intergenerational transmission including epigenetic changes and genetic memory, and more, all of which are constant, involuntary, and generally non-conscious. This article explores mutual imbeddedness: its pathways, its temporal sweep, its wide spectrum from trauma to beneficence, how it vitiates the binary of nature versus nurture, our capacity to meliorate its traumatic constrictions, and its meaning for our situatedness in death.