There has been relatively little inter-disciplinary work in the areas of loss, creativity, and the survivor. This article has a twofold aim: to compare within a clinical framework some expressions of grief in the creative literature of survivors, particularly of the Holocaust, and of literature depicting grief in more normal circumstances; and to explore the role of creativity as a response to personal and collective loss. Creativity in the wake of loss is treated as a means by which the bereaved, whether in normal conditions or following massive catastrophe, may struggle to express and to master his grief and, in doing so, find meaning in continued life.