This fine collection of articles documents efforts to bring Anna Freud’s diagnostic profile (1965) up to date by integrating more recent theory and research in attachment theory, inter-subjective theory, and theories deriving from the work of Bion on the process of “containing” (Bion, 1988). While some of the articles present the theoretical context for this integrative effort, Melandri’s (this issue) thoughtful and comprehensive clinical case shows us how an updated diagnostic profile can be put to work in the consulting room.