The MindBrain Consortium is a society-affiliated program based at Summa Hospitals in Akron. The program is likely to become more regionalized. We have been doing studies on the neuropeptides of attachment and social pain. One was an inconclusive study on oxytocin, We are about to do a study using a partial mu-agonist, buprenorphine, as an adjunct for treatment of refractory depression. We know that the opioid system is intimately involved in quelling separation distress, depression, social pain, and physical pain. In collaboration with the Medical University of South Carolina and Ziad Nahas, we are in the final stages of writing up an fMRI study involving oxytocin and mentalization in depressed subjects. Our findings are fascinating, as they suggest that depressives “utilize” oxytocin in a less integrated, more cognitively oriented fashion relative to healthy controls. In this study, we use a version of Simon Baron Cohen's Reading the Eyes Task that was developed for autism and theory of mind.