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In the target article, Salas and Yuen use the same tools proposed by Kaplan-Solms and Solms (KS-S) – exploring the psychodynamic effects of neurological lesions – to extend their original hypothesis on the role of the frontal lobes in the mental apparatus. Salas and Yuen describe the results of brain injury in a patient with a more anterior lesion than the cases described by KS-S, noting that, unlike the effects of more posterior damage, anterior damage does seem to affect the mental apparatus, having particular impact on emotion regulation. The target article demonstrates the fruitfulness of the clinical neuropsychoanalytic approach, and this commentary speculates on why more of this work has not been published, and reflects on what it offers.