A young woman with intense longing for love was unable to satisfy these desires by a normal sexual relationship with a man because of her fears and inhibitions. She developed urticaria at those times when her longings were especially stimulated and frustrated. Twelve attacks were observed during analysis and their emotional settings described. Eight of them occurred in connection with dreams. These dreams invariably ended on the verge of frustration in an 'almost but not quite' situation. The urticaria appeared when weeping was repressed and often terminated when the patient wept. The findings were confirmed by a second analyzed case and by a few observations on five cases seen in interview. In connection with other observations, particularly on asthma, they led to the supposition of a possible relationship between certain states of allergic sensitivity and states of intense frustrated longing.