Reactions to hypnotics and anæsthetics in the waking state, dreams during the resultant sleep and psychosomatic reactions upon awakening, presented some consistent features as well as elements which varied with the patient's current emotional constellation. The effects of sodium amytal, taken as a sedative by one patient, were usually a decrease in anxiety and ensuing sleep. At other times it resulted in an increase of anxiety and anger. In another patient who received nitrous oxide anæsthesia during dental treatment, the consistent elements reflected the patient's struggle against the loss of her faculties of perception and mastery. The dream content and the concomitant feelings as well as the psychosomatic phenomena—laughter, weeping, and vomiting—varied with the different aspects of the unconscious problems with which the patient was struggling.