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The investigation presented in this monograph was a research project of the Chicago Institute for Psychoanalysis. Histological and psychological studies were combined in an effort to correlate endocrine function and psychodynamic processes. The investigators, working independently, studied the vaginal smears and basal body temperatures, and made simultaneous psychoanalytic observations on the emotional life of fifteen women of child bearing age. The findings were then compared. One hundred and fifty-two menstrual cycles were observed, embracing 2,261 days of observation.