Mescaline is a cortical stimulant which produces psychotic manifestations such as visual hallucinations, bizarre somatic sensations, depersonalization, persecutory ideas, affective disturbances and loss of insight. Hoch compared the reactions of normal persons and schizophrenics after receiving injections of this drug. The normal individuals displayed little anxiety or apprehension during the experiment; in the pathological group, there was a disposition to reveal more clearly the existing schizophrenic symptomatology as well as material—such as preoccupation with homosexual conflicts—which had not previously been verbalized. Among 'pseudoneurotic' schizophrenics, whose