In an attempt to determine prognostic criteria for insulin shock therapy of schizophrenia, Cohen subjects seventeen factors to statistical analysis in a series of one thousand cases. Weight and duration of illness were the only

significant factors found. Patients who gain over thirty pounds of weight during treatment were found to do twice as well as those who gain less than thirty pounds. This correlates with the observation that patients who lose weight immediately prior to the onset of a psychosis have a better prognosis. Patients sick less than one year did approximately twice as well as those sick more than one year.