A correlation between breast-mouth-hand reactions is postulated as the background of Raynaud's disease. The motor and sensory cortical areas for mouth and hand are closely linked and in evolutionary development the hand is a symbolic extension of the mouth. 'By derivation the breast is likewise integrated with the mouth and hence with the hand.' These relationships are also reflected in language and literature. Strong inhibition of oral (and consequently, in some individuals, of motor) aggression may be thus reflected in autonomic disturbances of the hands with the development of Raynaud's disease.