Gantt states that our authority on the effect of alcohol on sexual function is still Shakespeare. There is an absence of experimental work. Five dogs are used in the present investigation which demonstrates that in dogs alcohol delays the onset of ejaculation and shortens the duration of erection in proportion to the amount of alcohol used. Alcohol has a depressing effect on cortical and subcortical reflexes; in small doses it causes an increase in the latent period, and in larger doses a marked decrease of the intensity of the conditional reflexes and, to a less extent, of the unconditional reflexes. Differentiation was impaired and there was a marked variation of response depending upon the susceptibility of the dog (temperament or constitutional reactivity of the animal). The results of the study do not contradict the popular conception that alcohol increases desire but diminishes potency. Though clinical correlation is not the purpose of the paper, Gantt suggests that in regulated doses alcohol might have a therapeutic effect in impotence and