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The first edition of this book was published in 1942. Since then numerous discoveries have been made. The author has incorporated and applied all the new investigations in the study of neuroanatomy. The slice reconstruction method, three dimensionally developed by the author in the first edition, has been continued and further elaborated in this book. The three dimensional reconstruction proved of special value in the study of the medullary centers of the cerebrum and cerebellum. The lack of illustrations of gross anatomy of the brain in the first edition has been corrected by brain dissections planned with regard to the systemic unity and functional importance of the parts. To enhance the visualizations of entire systems, the author introduces schematic drawings on the 'half shell'. This method was applied for the first time in reconstructions to the study of the hypothalamic nuclei. The book is amply illustrated and at the end there is a laboratory study and a valuable atlas of sections and slice reconstructions in the form of beautiful drawings and photographs. In his discussion of the various nuclear components, systems and pathways, the author dwells at the end of each chapter on the neurophysiological and