The authors present their experiences with group therapy of patients with multiple sclerosis. The group, which required careful choosing and narrowing down, finally consisted of five women and two men, each of whom attended about fifty hour-and-a-half sessions held once a week. A striking discrepancy often existed between the degree of physical disability and that of psychic crippling. The somatization of anxiety was accompanied by constant seeking of a scapegoat as the cause of illness. Aggression was frequently expressed by difficulties at home, as well as by projection upon others. Exaggerated submissive compliance and excessive cordiality often covered underlying hostility or depression. Verbalization of feelings within the group often resulted in a reversal of these mechanisms as well as in the abandonment of secondary gains and of the dependent position which the illness fostered.