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This number of Psychosomatic Medicine reports a symposium on 'recent knowledge and theories of the physiology of the central and autonomic nervous systems and of the endocrine apparatus from the point of view of their joint relationship to psychosomatic phenomena in general'. The symposium discusses the Brain Stem Mechanism (Robert V. Livingston), the Limbic System (Paul D. MacLean), the Hypothalamic Endocrine System (R. A. Cleghorn), Respiratory Mechanisms (Ely G. Goldenson), Levels of Awareness (Robert G. Heath), and Symbolic Functions (Mortimer Ostow). An interpretative commentary and summary is presented by Gilbert H. Glaser. These articles are highly recommended for those interested in the current attempts to correlate physiological and psychological functions.