The authors studied thirty-two women with lymphocytic, myelocytic, or monocytic leukemia, Hodgkin's disease, reticulum-cell sarcoma, and lymphosarcoma. They included four types of personality: mothering, clinging, isolated, and manly. All seemed to have unresolved attachments to their mothers. One of the multiple conditions determining the development of lymphoma or leukemia may be separation from a key object or goal with an ensuing depression. These women had suffered various types of losses and separations in a four-year period prior to the apparent onset of the disease; half of these occurred during the one-year period before the apparent onset. Change of home and natural or surgical menopause are considered losses, as are the more obvious losses of significant persons by death or illness. The personalities of these patients,