This work is already familiar to those American readers who have read Ostow's 1962 volume on combining drugs and psychotherapy. In attempting to correlate the effects of psychotropic agents and mental functioning, the author categorizes the changes produced in ego and drive characteristics. In the libido plethora syndrome he describes three main functions: first, the ego supplement, i.e., the energic state of the ego as manifested in various euphoric or dysphoric expressions; second, increased erotism; and third, object relations. The report is based on twelve patients in therapy who were given drugs, and one patient who recovered from melancholia into hypomania after a year in analysis without medication.