The author states that negative therapeutic reaction results from rage and destructiveness deriving from and exercised against pathological introjects. It is a depressive, sadomasochistic rage projected and induced in another person as a desperate effort at defense against expectation of inner loss and helplessness. It is essential that the analyst have a capacity for empathic identification with these patients and have worked through his own projective distortions and sadomasochistic defenses. By recognizing and not yielding to the patient's projections of guilt and depression he becomes a guilt-free introject, thus strengthening the patient's nonmalevolent and accepting potentialities. The final therapeutic task is the analysis of primary identification with the depressed, preoedipal mother.