DISCUSSION: Dr. Robert Dickes pointed out that because of the lack of physical data necessary for validation, it is difficult to evaluate the significance of the cases reported by Dr. Jackel in terms of causal relationship even though there is a temporal sequence. He emphasized the need for accumulating further evidence such as Dr. Jackel's until the information passes the point of coincidence. Dr. Emanual Klein felt that there is no doubt that many colds are preceded by depression and that in some manner colds are a way of warding off or getting over depression. Dr. Alan Eisnitz reported on two female patients, both with unusually intense pregnancy fantasies, who developed colds during analysis. Dr. Max Schur pointed out that herpetic lesions which are definitely viral may be produced under hypnosis and that the common wart, also viral, can respond favorably to suggestion. He questioned, however, whether some patients did not try to abort a cold by taking 'cold tablets', to which many people respond with mild depressive feelings.