Many patients who suffer from borderline personality disorder seem to respond well to various classes of psychopharmacologic agents, and almost two-thirds of outpatients with this diagnosis receive some sort of medication. The tendency of these patients to idealize one form of treatment and denigrate all others at a given time creates difficulties for a multidisciplinary approach to their cases. It is therefore essential to explain clearly to borderline patients that their condition has both psychological and biological sources. There is as yet no systematic way of determining which medication will be helpful to a particular patient; this must still be ascertained by trial and error. Berger summarizes the facts that have been gathered to date on both the frequently employed and the experimental agents, and makes some suggestions which may prove useful to the clinician who is relatively inexperienced in this area of psychiatry. The list of references is brief, but they are well selected and comprehensive.