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This brief note introduces a memoir by Robert S. Wallerstein, M.D. Wallerstein’s essay reviews his career, beginning as an internist and soon as a psychiatrist–psychoanalyst. Wallerstein’s professional account of his development tracks the historical periods within which it unfolded. This reflects his own social and political awareness, which was expressed in the activist spirit that vitalized his work within established medical and psychoanalytic institutions.