The serious consideration of paranormal phenomena, or psi, has not been scientifically respectable in modern intellectual discourse. A skeptical attitude persists despite robust evidence demonstrating the reality of nonlocal phenomena such as telepathy and the impact of mind from a distance. A major obstacle to the thoughtful consideration and integration of this evidence is the fact that paranormal phenomena do not fit within generally accepted models of how the universe works. Newer constructs and research findings in quantum physics, however, demonstrate the reality of nonlocal effects and help provide a conceptual framework that encompasses the research documenting psi. Paranormal phenomena have relevance for the fields of psychotherapy and psychoanalysis in the consideration of nonverbal communication and mutual influence between therapist and patient.