Advances in neuroscience make it possible to view the construction of meaning as a biological property. Freud's Project for a Scientific Psychology in which emotion and memory form a seamless unified system is seen as an attempt to establish psychoanalysis as a neurobiology of meaning. In the unconscious construction of meaning, metaphorplays a salient role; metaphor is the currency of mind. I have suggested that metaphor functions unconsciously as a pattern detector and thus plays a dominant role in the organizing and categorizing of emotional memory. Consideration of the evolution of the limbic system enables us to make a functional distinction between unconscious emotional memory and conscious feelings. These observations should lead to a revision of our current psychoanalytic theory of affects.