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Infant’s volition has not been explored in healthy development. Our research conducted on the environmental response to infant’s initiatives (Hoffmann, Popbla, and Duhalde, 1998) shows that maternal attitude has a direct correlation with successful development of initiatives in infants aged 4 to 12 months, having implications for the capacities of infants to unfold as much as endowments allow. The opposite also is true. Infants who are more thwarted in the development of their potential initiatives show greater reactivity and conflict in early relationships with the caregiver, impacting the development of a healthy self. These claims will be discussed with proposals made in recent decades by some authors who have focused on the coming together of a self in the first year of life. The ramifications of this early start in one’s life can be credited to Lou Sander, whom we honor in this issue. Sander was gifted with a capacity to see with a “relational eye” and to state it in everyday language, while simultaneously using very sophisticated inventions to validate his assumptions. This work has made it possible to solve the riddle of the David and Goliath story that is part of the miracle of life over death, of love over hate, of health over sickness, which makes (most) mothers able to become good enough or whatever defines a progressive meeting between the infant’s doings with the doings of mothers.