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Details of Freud's 5-year treatment of a male patient are reconstructed from the Wilhelm Fliess correspondence. The patient, “E.,” links Freud's therapeutic work and his self-analysis during the transition years between 1895 (Studies on Hysteria) and 1900 (The Interpretation of Dreams). The use of material from “E.” 's therapy in The Interpretation of Dreams—the patient's dream of being arrested for infanticide, and Freud's own dream stemming from criticism of the 5-year length of “E.” 's treatment—links “E.” 's therapy to Freud's own anxiety-neurotic difficulties in the late 1890s and to the nascent theories of neurotic etiology, psychoanalytic interpretation, and transference.