This article explores the relationship between concept of object loss and mourning and the loss of a bodily part or psychological or physical function in a rehabilitation context. The psychoanalytic literature on object loss and the mourning process is reviewed and related to existing literature on the adjustment-to-disability process. Similarities and differences between the classical mourning process and the adjustment-to-disability process are discussed, and suggestions are offered for using psychoanalytic strategies to facilitate adjustment to disability.