This study examined the relationships between defenses and depressive experiences. Two questionnaires, in counterbalanced order, were administered to a community sample of 205 adults: the Depressive Experiences Questionnaire (DEQ; S. Blatt, J. D'Afflitti, & D. Quinlan 1976, 1979) and the Defense Mechanisms Inventory (DMI; D. Ihilevich & G. C. Gleser, 1986). Although turning against self related significantly to both depressive experiences of dependency, especially the less mature neediness in comparison with the more mature connectedness, and self-criticism, other types of defenses, as measured by the DMI, differentiated between interpersonal and self-critical experiences of depression. Results are discussed from psychodynamic and developmental perspectives.