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The Psychodynamic Diagnostic Manual–2 challenges the constraints of traditional nosographic frameworks by offering clinicians a comprehensive guide for case formulation. This article aimed to underscore the significance of these features within the sensitive context of developmental psychopathology. The Psychodynamic Diagnostic Manual–2's capacity to not only provide a nuanced clinical perspective that captures an individual's functioning in a holistic and integrative manner but also to guide the development of personalized treatment plans is particularly emphasized. Through a clinical case study, this article aims to discuss assessment methodologies. Psychodynamic Diagnostic Manual–2 compares data derived from psychometric testing with insights from clinical observation while contextualizing these findings within the patient's specific developmental phase.