Infants are liable to many symptoms of emotional disturbance. However, it is now widely agreed that there is no such thing as individual psychopathology in infancy. Infantile disturbances are considered to be a function of current relationships. The paper briefly summarises available psychodynamic approaches to problems in infant relationships. It argues that more case-studies of therapeutic interventions in infancy are needed to increase our understanding of early disturbances and of their treatment. Two contrasting case-studies of intervention in persistent crying attempt to understand what may sustain this distressing problem. In each case the possible meaning of the crying, both to the babies and to their families, is considered.