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This article provides a description of the development and work of The Fitzjohn’s Unit a specialist service, housed within the Adult Department of the Tavistock and Portman NHS Foundation Trust, providing psychoanalytic psychotherapy for patients suffering from the more complex/serious disorders many of them having been unwell for many decades. The paper describes the patients treated, the model of care and also aims to show how this work can illuminate more general consideration such as the nature of the psychoanalytic attitude and the relation of psychiatry to psychoanalysis