There are many aspects—political, economic, legal, medical, cultural, religious—of the present refugee crisis in Europe. Difficulties at border crossings, settlement programs, life-saving issues, and security measures come to mind immediately, but the refugee crisis also needs to be examined from a psychological angle. This paper outlines psychoanalytic findings on voluntary and forced immigration and human responses to the Other. Change in the twenty-first century is occurring at an unprecedented pace and scale. Globalization, incredible advances in communication technology, fast travel, recourse limitations, terrorist activities, and now the refugee crisis in Europe make psychoanalytic investigation of the Other a necessity.