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As transsexual and transgender identity and experience have emerged from the outer boundaries of sexual identity and have become part of mainstream awareness of the full potential for sexual self-definition, cultural response has ranged widely. Responses include acceptance and approval; moderate levels of anxiety concerning perceptions of gender, sexual identity, and sex; obsessive fascination with the “otherness,” the “not-me-ness” of those identifying as transsexual or transgender; the desire of non-trans-people to co-opt the experience of trans-people without personal risk; alarm at the reification of gender roles in what some people hoped would be a non-gender-defined, gender-neutral future. And more.