The pleasure and danger of sexuality thematizes erotic desire as always accompanied by a certain anxiety. Although some anxiety is material and precautionary, I address the issue somewhat differently through investigating the psychic factors at play in the western imaginary. Discomfort with manifestations of erotic desire is most clearly invoked by differential embodiment where the challenge to the normative body not only results in disqualification from discourses of sexuality but also raises the contested question of who is to count as a sexual subject. My purpose is not to inquire empirically into the ways that people with disabilities are denied sexual subjectivity but to ask what is at stake in the cultural imaginary that requires such a closing down of possibilities. I develop a psychoanalytic approach to sexually marked anomalous embodiment and ask what part the link between desire and lack plays in thwarting a positive model of disability and sexuality.