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This article introduces the portfolio of essays on Paul B. Preciado’s Testo Junkie: Sex, Drugs, and Biopolitics in the Pharmacopornographic Era (2013). After briefly describing the project of that book, the essay explains the history of the public forum and, now, publication in which Preciado was in conversation with 3 clinicians: Kirsten Lentz, Carolyn Stack, and Jamieson Webster.