The psychological and sociopolitical significance of Freud’s 1905 assertion of polymorphous perversity and originary bisexuality as being the source of all human sexual expression is explored. The way in which normative sexual development involves a trajectory of loss of our capacities for sensual pleasure is discussed. The notion of humans as all having “polysexual potential” is introduced, and it is argued that appreciating polysexuality as a central feature of our condition has emancipatory value and is thus preferable to the pejoratively toned terminology that Freud deployed.