In this article I examine the ways in which trans and gender nonconforming people are produced as both a sensitive and triggering “issue,” particularly through sensitization practices that are characteristic of LGBTIQ+ diversity training. I discuss the work that different modalities of the sensitive do in the clinic and training of cisgender professionals by bringing together research materials from fieldwork in Chile. In doing so, I show how sensitivity sticks to trans people by making them vulnerable to medical gatekeeping practices, which end up producing a particular way of knowing the other marked by what I call the “anxiety to know,” reproducing forms of gender panic that construct nonnormative genders as still needing an explanation. My discussion joins the call of scholars and activists who interpellate cisgender practitioners to account for our own gender anxieties as a means to facilitate an encounter with opacity that might trigger a desire to know more about our gender nonconformity.